Instant recognition: the genetics of pitch perception

Article Abstract:

A substantial genetic component underlies the development of what is commonly called perfect pitch, that is, absolute pitch, based on an overall view of available data. Prevalence of AP in various populations is not known precisely. Evidence seems to show that childhood exposure is a factor in AP phenotype. It appears that some subset of those with AP also have exceptional mathematical/memory ability and that in rare cases those with AP have unusual perceptual acuity, perhaps in taste and a few who have AP associate certain colors with certain pitches, called synesthesia. Research into the area of AP is a start into research into brain development, cognition and early childhood education.

Causes of, Autism, Synesthesia, Musical ability

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Absolute pitch: an approach for identification of genetic and nongenetic components

Article Abstract:

Research to try to separate influences of early music training and genetics on Absolute pitch (AP) development has been carried out. Early music training is apparently necessary, but not sufficient, for AP development. Those who self-reported that they had AP were 4 times as likely as others to report another AP person in their families. Several families suitable for studies of the genetic basis of AP have been identified. A simple computer-based acoustical test was used to subdivide those with AP into groups based on performance on the test and 600+ musicians were surveyed initially. AP is ability to recognize pitch with no external reference.

Observations, Musicians

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Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18

Article Abstract:

The feasibility of using linkage disequilibrium analysis in genome screening for complex disorders was supported in a study of severe bipolar mood disorder (BP-I) in Costa Rica. Genotyping of chromosome 18 was done at intervals of about 6 cM for 48 subjects with BP-I. Previous linkage studies had identified chromosome 18 as a possible site for bipolar disorder loci. Possible susceptibility regions were identified by the screening.

Costa Rica, Bipolar disorder, Linkage (Genetics)

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