Mitochondrial death throes: Knockout mice reveal a path to necrosis

Article Abstract:

Studies indicate that the mitochondrial protein cyclophilin D (CyPD) could mediate the transition to mitochondrial permeability that leads to necrotic cell death. Mitochondria in cancer cells have shown strong resistance to calcium ions and do not easily open their necrotic pores, a characteristic which could be used to make drugs that target the cancer mitochondria and leave the regular mitochondria alone.

Mitochondria, Cyclophilin

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Remodeling the model T

Article Abstract:

The functions and the T cell lineage suppression of the newly developed class of T helper cell, [T.sub.H]17 cells are discussed. The cell is found to be helpful in recognizing and extenuating the tumor growth in humans.

Cell differentiation, Transforming growth factors

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Solving the viral spike

Article Abstract:

The viral spike, a trimer of glycoproteins (gp120 and gp41) as a invasion strategy for blocking infection that help fuse the envelope to the receptor CD4 and T cells is reviewed.

Usage, Glycoproteins, X-ray crystallography

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