Molecular development of sensory maps: representing sights and smells in the brain

Article Abstract:

An analysis of the mapping mechanisms that control the orderly representation of peripheral sense organs in the brain was conducted among chicks, rodents and mice. Results show that the map onto the olfactory bulb is virtually unknown which presents difficulties that hinder speculation about mapping in the olfactory system. There are distinctions in the anatomical and functional requirements of the olfactory and retinotectal systems. However, they also display substantial differences with regards to their orderly axonal projections.

Brain research, Olfactory nerve, Sensory stimulation, Optic nerve

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Inductive tissue interactions, cell signalling, and the control of kidney organogenesis

Article Abstract:

In 1901, Hans Spemann showed that lens development depends on inductive signals from the optic cup to the presumptive head ectoderm. Clifford Grobstein established the kidney as a model system for studying organogenesis in the 1950s. Kidney development has been thought to depend on sequential and reciprocal inductive interactions. Experiments providing genetic evidence for the sequential and reciprocal nature of inductive interactions are discussed and molecular models for the different stages of kidney organogenesis are provided.

Kidneys, Tissues, Tissues (Anatomy), Kidney

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