Move it on over: getting proteins across biological membranes

Article Abstract:

This article discusses the translocation of macromolecules such as proteins across biological membranes. Research shows that the translocation system varies in composition depending upon whether it is signal-gated or signal-assembled. The system deploys components that are unique to the system such as translocons and translocon helpers.

Israel, Biological transport, Cell membranes

---

Investigating protein-protein interfaces in bacterial transcription complexes: a fragmentation approach

Article Abstract:

Research examines a novel sequence within sigma(sup)54-dependent transcriptional activators making up a sigma(sup)54-binding interface. Data indicate that this binding interface is dynamic and exhibits nucleotide-dependent movement that controls output of ATPases associated with various cellular activities (AAA+) proteins.

United Kingdom, Analysis, Gene expression, Genetic transcription, Transcription (Genetics), DNA-ligand interactions, DNA binding

---

The spliceosome: the most complex macromolecular machine in the cell?

Article Abstract:

The ribonucleoprotein complex spliceosome, involved in the splicing of introns, is composed of 300 proteins and five RNAs. It is the most complex macromolecular machine and the complexity is due to its criticl role in catalysis, quality control role(s) in mRNA synthesis, and its links to other nuclear machines.

United States, Product quality, Quality management, Protein synthesis, Protein biosynthesis, Messenger RNA, Introns

Similar abstracts:

• Abstracts: Role of competition for inorganic nutrients in the biodegradation mixtures of substrates. Influence of calcium, iron and pH on phosphate availability for microbial mineralization of organic chemicals
• Abstracts: More than the sum of their parts: on the evolution of proteins from peptides. How to tweak a beak: Molecular techniques for studying the evolution of size and shape in Darwin's finches and other birds
• Abstracts: The calpain-system of Drosophila melanogaster: Coming of age. A bigger mouse? The rat genome unveiled
• Abstracts: Operating under a Gag order: a block against incoming virus by the Fv1 gene. Reverse transcriptase of moloney murine leukemia virus binds to eukaryotic release factor 1 to modulate suppression of translational termination
• Abstracts: Participation of women in human biology. Life history and the early origins of health differentials. Mixed-longitudinal analysis of growth data from Malian adolescent girls: evidence for compensatory gain?

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.