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Neanderthal DNA sequences and the origin of modern humans

Article Abstract:

A series of DNA specimens that were extracted from the right humerus of aNeandertal-type specimen was analyzed by amino acid racemization and DNA amplification techniques to characterize the its DNA patterns. DNA amplification of the Neanderthal samples indicated the presence of an amplification product that was composed of two classes of sequences. Pairwise amino acid sequence comparisons of the mitochondrial DNA indicated the wide genetic differences between modern humans and neandertals.

Author: Paabo, Svante, Stoneking, Mark, Krings, Matthias, Stone, Anne, Schmitz, Ralf W., Krainitzki, Heike
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997

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Facts and artifacts of ancient DNA

Article Abstract:

Neandertals once characterized as a an ancient race of human beings that wer genetically absorbed into the population of Homo sapiens through cross-breeding. However, genetic analysis of Neandertal mitochondrial DNA indicated the absence of amino acid sequence similarity between modern humans and the ancient species. Mitochondrial DNA analysis from samples collected in Neandertal bones also indicated the absence of similarity between the modern human genome and the Neandertals.

Author: Lindahl, Tomas
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997

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mtDNA analysis of Nile River Valley populations: a genetic corridor or a barrier to migration?

Article Abstract:

Studies reveal a genetic migrational pattern among populations along the Nile River Valley. Using first hypervariable segment sequences of the control region of the mtDNA, coupled with a polymorphic Hpa1 site, researchers were able to determine the migrations to be between a few hundred to a few thousand years old, and predominantly from south to north.

Author: Paabo, Svante, Utermann, Gerd, Di Rienzo, Anna, Simon, Christian, Sajantila, Antti, Stoneking, Mark, Geisert, Helga, Bauer, Karin, Krings, Matthias, Salem, Abd-el Halim, Malek, Adel K., Chaix, Louis, Welsby, Derek
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1999
Egypt, Health aspects, Research, Demographic aspects, Genetic research, Egyptians

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Subjects list: Analysis, Genetic aspects, DNA, Human beings, Humans, Neanderthals, Neanderthal man
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