On a roll for new TRF targets

Article Abstract:

The identification of new TBP-related factor (TRF1) targets with three classes, TRF1, TRF2, and TRF3 is discussed. The three classes have contained a core domain related to the TATA-box-binding protein (TBP) C-terminal core domain and some have also possessed variable N- and C-terminal domains.

Genetic regulation, Genomics

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A structural perspective of CTD function

Article Abstract:

The structure, modification, and recognition of the C-terminal domain (CTD), from which insights into the molecular mechanism of CTD-mediated coupling were observed is reviewed. The CTD of RNA polymerase II (Pol II) integrates nuclear events by binding proteins involved in the mRNA biogenesis.

RNA polymerases

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Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature

Article Abstract:

Various lineage tracing studies are conducted to analyze the origin of the mammalian lymphatic vasculature, which has been a topic of debate since decades. Results show that the mammalian lymphatic system has a solely venous origin.

Tamoxifen, Lymphatic vessels

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