A model for population growth of laboratory animals subjected to marker-assisted introgression: how many animals do we need?

Article Abstract:

Methods have been developed for calculating the variance and mean of the number of animals with a desired genotype in every backcross generation for marker-assisted introgression experimentation. The goal is having animals homozygous for desired loci. The methods were developed for experiments with inbred lines and the model assumes Poisson litter size distribution. It is like that used in stochastic versions of population dynamics models. .

Australia, Laboratory animals, Biological models

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LOD significance thresholds for QTL analysis in experimental populations of diploid species

Article Abstract:

This article presents a method to ascertain exact loci in a genome and its bearing in identifying the gene that affects quantitative traits. The author proposes the term "suggestive linkage" for an objective comparison of results across species in qunatitative trait loci analyses.

Statistical Data Included, Analysis, Statistical hypothesis testing, Linkage (Genetics), Population biology

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