Reassessing the molecular biology of sperm-egg recognition with mouse genetics

Article Abstract:

A re-evaluation of the molecular basis of sperm-egg interactions in mammals is discussed. Research indicates that sperms without a hyaluronidase or acrosin, a proteolytic enzyme, are fertile. Furthermore, sperms that lack ADAM proteins cannot bind to the zona pellucida. Mouse models are presented.

Models, Physiological aspects, Genetic aspects, Eggs (Biology), Spermatozoa, Sperm, Fertilization (Biology), Zona pellucida, Egg (Biology)

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Boris Balinsky: Transition from embryology to developmental biology

Article Abstract:

The life of Boris Balinsky, a scientist and writer is presented by exploring the origins of his book 'An Introduction to Embryology'. He started his scientific career in the USSR, and ended it in South Africa due to the social and political agitations in the 20th century.

Evaluation, Works, Embryology, Experimental, Embryological research, An Introduction to Embryology (Book), Balinsky, Boris

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Divided loyalties: Transdetermination and the genetics of tissue regeneration

Article Abstract:

A study on the transdetermination can serve as a model for mechanisms of stem-cell commitment was conducted. The data provided suggests that pluripotency of cells within regenerating tissues is constrained by homeotic products.

Science & research, Research, Muscles, Muscle regeneration, Homeotic genes, Stem cell research

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