Recombination and the evolution of diploidy

Article Abstract:

A two-locus model was used to analyse the factors involved in the evolution of a dominant diploid state in organisms undergoing an alternation of generations. The results of the analysis showed that dipoidy will be favored whenever masking of deleterious mutations occur. However, this masking effect is highly dependent on the degree of free recombination. When the level of recombination is low, diploidy is less favored. The analysis revealed that even when the masking effect is strong, significant levels of recombination are still neccessary for diploidy to have evolved.

Analysis, Evolution (Biology), Genetic recombination, Evolution, Diploidy

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An evaluation of genetic distances for use with microsatellite loci

Article Abstract:

Use of the stepwise mutation model that incorporates allelic repeat score helps derive a genetic distance to be used with microsatellite loci. Application of the genetic distance to loci undergoing a strict stepwise mutation process reveals the linear relationship between the genetic distance and time. The reliability of this genetic distance is evaluated using computer simulations. The newly derived genetic distance is advantageous for phylogenetic reconstruction of taxa.

Models, Observations, Mutation (Biology), Mutation, Genetic research

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