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Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells

Article Abstract:

A study was performed to examine the feasibility of controlling compound exocytosis in mast cells via the transfer of t-SNARE SNAP-23 from lamellipodia-like cell surface projections. Results showed that the relocation will occur even without membrane fusion. Moreover, a subsequent secretory response will be expedited. The relocation will not only controls exocytosis but also links granule-granule fusions and granule-plasma membranes.

Author: Guo, Zhenheng, Turner, Christopher, Castle, David
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
Mast cells

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Calcium signaling networks channel plant [K.sup.} uptake

Article Abstract:

A protein complex is identified in Arabidopsis that consists of a potassium channel, a protein kinase and calcium sensor and potassium ions [[K.sup.}] are found to be an essential nutrient for plants. The analysis has shown that plants cope with limited soil potassium by coupling potassium channel activation to a cellular calcium signaling network.

Author: Hedrich, Rainer, Kudla, Jorg
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
Genetic aspects, Potassium channels, Arabidopsis thaliana

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Removal of Ca(super 2,+) channel beta (sub 3) subunit enhances Ca(super 2,+) oscillation frequency and insulin exocytosis

Article Abstract:

Oscillatory increase in pancreatic beta cell cytoplasmic free ca (super 2,+) concentration is studied. Since it is an important feature in glucose-induced insulin release, subunit of beta cell may constitute the basis of novel diabetes therapy.

Author: Murakami, M., Berggren, P.-O., Kohler, M., Moede, T., Fernstrom, A., Appelskog, I.B., Aspinwall, C.A., Yang, S.-N., Zaitsev, S.V., Larsson, O., Vargas, L.M.de, Fecher-Trost, C., WeiBgerber, P., Ludwig, C.J., Leibiger, B., Juntti-Berggren, L., Barker, C.J., Efanov, A.M., Gromada, J., Freichel, M., Leibiger, I.B., Uhles, S., Flockerzi,V.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
Frequencies of oscillating systems, Oscillating frequencies

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Subjects list: Research, Exocytosis, Calcium channels
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