Remembering Eva Neer

Article Abstract:

The life, career and accomplishments of Eva Neer, born in Poland and eventually becoming mother of two and a Harvard professor of biochemistry, are reviewed by a fellow heart researcher. Her work led to acceptance of the fact that G(sub.beta)(sub.gamma) activates as many effectors as does G(sub.alpha). She was an honest and courageous woman in the crusade to have this work accepted and she worked surveying the career paths of women at Harvard Medical School, fighting to make that environment more fair. She was fun to be with, as well.

Biography, Biochemists, Women scientists, Neer, Eva

---

Calcium signaling

Article Abstract:

Ionized calcium (Ca2+) forms the commonest signal transduction unit in cells and cytosolic Ca2+ level buffering leads to specialized Ca2+-binding domains in proteins. Incorporation of the binding domains into many proteins facilitates the action of Ca2+ as a triggering second-messenger element that activates effector molecules to undergo conformational changes. Depolarization of membrane potential regulates the action of Ca2+ as a signal transduction unit.

Analysis, Calcium ions, Cellular signal transduction

---

Symmetry, selectivity, and the 2003 Nobel Prize

Article Abstract:

This essay describes the discovery and elaboraion of ion channels in biological membranes and how each of the component regulate ions and water across the membranes via ion- and water channels based on symmetry and selectivity. The research was awarded the 2003 Nobel Prize to Rod MacKinnon and Peter Agre.

Science & research, Physiological aspects, Biological transport, Ion channels, Nobel laureates, Aquaporins

Similar abstracts:

• Abstracts: Responses of methanotrophic activity in soils and cultures to water stress. Methanol promotes atmospheric methane oxidation by methanotrophic cultures and soils
• Abstracts: Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket. Core structure of gp41 from the HIV envelope glycoprotein
• Abstracts: Role of calcium in activity and stability of the Lactococcus lactis cell envelope proteinase. Molecular and functional analyses of the metC gene of Lactococcus lactis, encoding cystathionine beta-lyase
• Abstracts: Molecular forensic profiling of Cryptosporidium species and genotypes in raw water. Comparison of animal infectivity and nucleic acid staining for assessment of Cryptosporidium parvum viability in water
• Abstracts: Differential damage in bacterial cells by microwave radiation on the basis of cell wall structure. Enhancement of secretion and extracellular stability of staphylokinase in Bacillus subtilis by wprA gene disruption

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.