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RhoBTB2 is a substrate of the mammalian Cu13 ubiquitin ligase complex

Article Abstract:

A model has been suggested wherein Rh0BTB2 functions as a tumor suppressor by recruiting proteins for degradation. More tests are being conducted to identify if Rh0BTB2 is indeed a substrate-specific adoptor for Cul3.

Author: Wilkins, Andrew, Carpenter, Christopher L., Ping, Qinggong
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
Proteins, Mammals, Ubiquitin

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Dictyostelium RasD is required for normal phototaxis, but not differentiation

Article Abstract:

Research has been conducted on the mammalian Ras Dictyostelium homolog RasD. Results indicate that gene distribution for rasD causes phototaxis and thermotaxis loss in mutant aggregates.

Author: Wilkins, Andrew, Khosla, Meenal, Fraser, Derek J., Spiegelman, George B., Fisher, Paul R., Weeks, Gerald, Insall, Robert H.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2000
United Kingdom, Statistical Data Included, Heredity, Oncogenes, Ras genes, Phototaxis

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A secondary disruption of the dmpA gene encoding a large membrane protein allows aggregation defective Dictyostelium rasC? cells to form multicellular structures

Article Abstract:

The development of multicellular structures by Dictyostelium rasC-cells due to disturbance of the dmpA gene is studied.

Author: Khosla, Meenal, Spiegelman, George B., Weeks, Gerald, Parent, Carole A., Kriebel, Paul
Publisher: Elsevier B.V.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
United States

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Subjects list: Research, Genetic aspects, Canada, Dictyostelium
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