SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates?

Article Abstract:

Structural maintenance of chromosome (SMC)-mediated chromosome mechanics may be a conserved scheme from bacteria to vertebrates. Molecular mechanisms that underlie some structural changes of chromosomes have been not well understood. Research has shown a novel family of chromosomal ATPases, the structural maintenance of chromosome family, exists. Two distinct classes of SMC protein complexes, cohesins and condensins, have major roles in sister-chromatid cohesion and chromosome condensation, respectively.

United States, Analysis, Evolution (Biology), Evolution, Chromosomes

---

Dynamic molecular linkers of the genome: The first decade of SMC proteins

Article Abstract:

The mechanistic action of structural maintenance of chromosomes (SMC) machines and the repertoire of their cellular functions are studied. The analysis of these SMC proteins complex would make great contributions to the understanding of basic mechanisms of SMC action and the evolution of he SMC-mediated segregation machinery.

Proteins, Protein structure

---

The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends

Article Abstract:

The impact of the structure of the broken DNA ends on the pathways and outcomes of the mycobacterial nonhomologous end-joining (NHEJ) system is discussed. The outcomes of the NHEJ are found to be highly dependent on DNA double-strand breaks, as well as the ensemble of the end-processing and end-sealing components.

Eukaryotes, Mycobacteria, DNA binding proteins, Mycobacterium

Similar abstracts:

• Abstracts: Chromosome ends: Different sequences may provide conserved functions. Prospects and implications of using chromatin insulators in gene therapy and transgenesis
• Abstracts: Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes
• Abstracts: Anaerobic nitrate-dependent oxidation of U(IV) oxide minerals by the chemolithoautotrophic bacterium Thiobacillus denitrificans
• Abstracts: Tibetan protection from intrauterine growth restriction (IUGR) and reproductive loss at high altitude. Birth weight Tibetans at different altitudes in India: Are Tibetans better protected from IUGR?
• Abstracts: Age-related changes in testosterone and SHBG among Turkana males. Catch-up reproductive maturation in rural Tonga girls, Zambia?

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.