Selection on MHC-linked microsatellite loci in sheep populations

Article Abstract:

The diversity of microsatellite loci within or in close proximity of the major histocompatibility complex (MHC)-genes in several breeds of domestic (Ovis aries) and the wild (Ovis orientalis musimon) were assessed. Result showeds that for most breeds, the distribution of alleles at the MHC-linked microsatellites are more than the expected if the genes were neutral and sampled from population under drift-mutation equilibrium.

Gene mutations, Gene mutation, Allelomorphism, Alleles

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A long-term genetic survey of an ungulate population reveals balancing selection acting on MHC through spatial and temporal fluctuations in selection

Article Abstract:

A 13-year genetic survey of the major histocompatibility complex (MHC) and neutral loci of the soay sheep population of St.Kilda was examined to test the existence of and causes of balancing selection at the MHC. The comparisons of spatial and temporal divergence at MHC and non-MHC loci provide strong evidence of balancing selection at the MHC, acting through spatial and temporal heterogeneity in selection pressure.

France, Physiological aspects, Adaptation (Physiology), Physiological adaptation

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Quantitative trait loci associated with parasitic infection in Scottish blackface sheep

Article Abstract:

Quantitative trait loci (QTL) associated with endoparasitic infection in Scottish Blackface sheep is identified. The results show that some aspects of host resistance to gastrointestinal parasites are under strong genetic control, hence these QTL could be utilized in a marker-assisted selection scheme to increase host resistance to gastrointestinal parasites.

Analysis, Host-parasite relationships

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