Small-subunit rRNA genes and in situ hybridization with oligonucleotides specific for the bacterial symbionts in the larvae of the Bryozoan Bugula neritina and proposal of "Candidatus Endobugula sertula."

Article Abstract:

The small-subunit ribosomal RNA gene sequence of the bacterial symbionts of larval Bugula neritina was analyzed to determine phylogenetic affiliations of the symbionts. Hybridization studies using probes specific for the small-subunit ribosomal RNA gene sequence reveal that the bacterial symbionts are new species belonging to the gamma-proteobacterium. The proposed name for this larval Bugula symbionts is Candidatus Endobugula sertula.

Bacteria, Identification and classification, Species, Species (Biology)

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'Candidatus Endobugula glebosa', a specific bacterial symbiont of the marine bryozoan Bugula simplex

Article Abstract:

The bacteria in the pallial sinuses of Bugula simplex larvae was identified and whether polyketide synthase (PKS) genes and bryostatin-like polyketides were present in the organism was determined. The reports demonstrate a symbiosis in B. simplex that is similar and evolutionarily related to that in B. neritina.

Science & research, Polyketides, Candida

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Evidence for the biosynthesis of bryostatins by the bacterial symbiont "Candidatus endobugula sertula" of the bryozoan Bugula neritina

Article Abstract:

Researchers show that a family of macrocyclic lactones called bryostatins are produced by a bacterial symbiont of Bugula neritina, not by the bryozoan itself. These genes could be introduced into other bacteria so the bryostatins could be produced industrially because they have anti-cancer activity.

Antineoplastic agents, Bacterial proteins

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