Characterization of growth and acid formation in a Bacillus subtilis pyruvate kinase mutant

Article Abstract:

Results show that pyruvate kinase mutants of Bacillus subtilis do not produce acid, instead produce increased amount of carbon dioxide and reduction in growth. Data reveal that high production of phosphoenolpyruvate and glucose-6-phosphate retard bacteial growth.

United States, Statistical Data Included, Physiological aspects, Growth, Bacteria, Carbohydrate metabolism, Microbial mutation

---

Engineering of Bacillus subtilis for enhanced total synthesis of folic acid

Article Abstract:

A study investigated whether the yield of the B vitamin folic could be elevated in Bacillus subtilis. Controlling the activity of the enzyme pyruvate kinase by placing it under inducible control is one strategy devised to elevate yield while insuring that a rapid growth rate results.

Science & research, All Other Basic Organic Chemical Manufacturing, Enzymes, Other Basic Organic Chemical Manufacturing, Enzymes for Food Processing, Folic acid, Chemical properties

---

Supply-side analysis of growth of Bacillus subtilis on glucose-citrate medium: feasible network alternatives and yield optimality

Article Abstract:

The processing of glucose by Escherichia coli network leads to conflicts between maximizing carbon or ATP yield, with maximal theoretical carbon yield being less than .80 of cell C/g of glucose C. Nonoptimal flux regulation contributes significantly to apparent cellular maintenance requirements. Elevated carbon yield can be attained without the alleviation of citrate-glucose utilization-induced stoichiometric constraints, which can interfere with the attainment of network objectives. The high carbon yield and nil acid formation are linked to restriction of glycolytic capacity.

Carbon, Glucose metabolism

Similar abstracts:

• Abstracts: Structural analysis of Bacillus megaterium KM spore peptidoglycan and its dynamics during germination. Complete spore-cortex hydrolysis during germination of Bacillus subtilis 168 requires SleB and YpeB
• Abstracts: Sequence and RFLP analysis of the elongation factor Tu gene used in differentiation and classification of phytoplasmas
• Abstracts: Effect of ammonia production by Colletotrichum gloeosporioides on pelB activation, pectate lyase secretion, and fruit pathogenicity
• Abstracts: Analysis of aberrant virulence of Gibberella zeae following transformation-mediated complementation of a trichothecene-deficient (Tri5) mutant
• Abstracts: Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.