The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte

Article Abstract:

A study of ATP concentrations in the oocyte at the time of gonadotropin-activated- and spontaneous maturation reveals that the gap junction-dependent relation of meiotic arrest is related to glucose-stimulated ATP level enhancement. Spontaneous maturation occurs through a stoppage of inhibitory regulation while ligand-activated maturation occurs through the formation of a positive stimulus of cumulus cell origin. Heterologous gap junctions transmit the positive stimulus to the oocyte, activating the breakdown.

Growth, Glucose, Oocytes, Oocyte donation

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High-molecular-weight protease complexes (proteasomes) of sperm of the ascidian, Halocynthia roretzi: isolation, characterization, and physiological roles in fertilization

Article Abstract:

Researchers isolated two types of chymotrypsin-like enzymes from spermatozoa of Halocynthia roretzi, and characterized them as high-molecular-weight protease complexes that contained many subunits and exhibited distinct protease activities. Both enzymes exhibited immunoreactivity with anti-proteasomes antibody. The results indicate that the proteasomes are exposed extracellularly when sperm contact with the egg coat, and may act as lysins in fertilization.

Research, Chymotrypsin

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KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation

Article Abstract:

The contribution of KATP (potassium-adenosine triphosphate) channels in the capacitation of mammalian sperms is studied. The series of physiological changes collectively known as capacitation, occur in the female reproductive tract, makes the sperm suitable for fertilization.

All Other Basic Inorganic Chemical Manufacturing, Mexico, Potassium, Industrial inorganic chemicals, not elsewhere classified, Mammals, Potassium (Chemical element)

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