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Molecular properties of bacterial multidrug transporters

Article Abstract:

Multidrug transporters are a major impediment in the care and treatment of patients as they confer resistance to several of the antibiotics that are in use now. This review discusses the genetic basis and physiological and molecular mechanisms governing the microbial antibiotic resistance are discussed.

Author: Konings, Wil N., Putman, Monique, van Veen, Hendrik W.
Publisher: American Society for Microbiology
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2000
Antibiotics, Microbial metabolism, Microorganisms

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The lactococcal secondary multidrug transporter LmrP confers resistance to lincosamides, macrolides, streptogramins and tetracyclines

Article Abstract:

Research has been conducted on the secondary multidrug transporter LmrP. The role of this transporter in the resistance to a variety of clinically important antibiotics used to fight infectious diseases has been investigated and discussed.

Author: Konings, Wil N., Putman, Monique, Veen, Hendrik W. van, Degener, John E.
Publisher: Society for General Microbiology
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2001
Prevention, Communicable diseases, Macrolide antibiotics, Macrolides, Tetracyclines, Lactococcus

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Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria

Article Abstract:

The distribution of ABC-type multidrug resistance (MDR) transporters in bacteria is analyzed. The analysis of MDR transporters has resulted in the construction of new generation of drug-hypersensitive strains.

Author: Konings, Wil N., Driessen, Arnold J.M., Lubelski, Jacek
Publisher: American Society for Microbiology
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2007
Science & research, Research, Genetic aspects, Glycoproteins, Gram-negative bacteria, Archaeabacteria, Gram-positive bacteria, Archaea

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Subjects list: Statistical Data Included, Analysis, Netherlands, Physiological aspects, Drug resistance in microorganisms, Microbial drug resistance, Microbiological research
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