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The medium-/long-chain fatty acyl-CoA dehydrogenase (fadF) gene of Salmonella typhimurium is a phase 1 starvation-stress response (SSR) locus

Article Abstract:

A study was conducted to analyze the medium and long-chain fatty acyl-CoA dehydrogenase gene of Salmonella typhimurium. The strains utilized in the study were derivatives of the Salmonella enterica serovar Typhimurium strain SL1344 or TR6583. Spontaneous fadR mutants of S. typhimurium were prepared by inoculating NCE agar medium. Results indicated that signals for induction are present in the intracellular environment encountered by S. typhimurium.

Author: Dougan, Gordon, Finlay, B. Brett, DiRusso, Concetta C., Pallen, Mark J., Spector, Michael P., Del Portillo, Francisca Garcia
Publisher: Society for General Microbiology
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1999
Dehydrogenases, Oxidoreductases, Fatty acids, Salmonella typhimurium

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Role of Bordetella pertussis P.69/pertactin protein and the P.69/pertactin RGD motif in the adherence to and invasion of mammalian cells

Article Abstract:

The P.69/peractin protein of Bordetella pertussis was analyzed to determine the mechanisms of cellular adhesion between the pathogenic microbe and mammalian cells. Isogenic parenteral strains are less invasive than Bordetella pertussis strains containing the prn gene which encodes the P.69/peractin protein. However, expression of the surface-associated P.69/peractin protein did not alter the invasiveness of Escherichia coli in mammalian cells.

Author: Dougan, Gordon, Roberts, Mark, Chatfield, Steven, Everest, Paul, Li, Jingli, Douce, Gillian, Charles, Ian, De Azavedo, Joyce
Publisher: Society for General Microbiology
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1996
Genetic aspects, Proteins, Bacteria, Pathogenic, Pathogenic bacteria, Cell adhesion, Bacterial proteins, Bordetella pertussis

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Evaluation of the intranasal challenge route in mice as a mucosal model for Candida albicans infection

Article Abstract:

Candida albicans infections in two strains of mice were studied using the intranasal route. Results showed that while DBA/2 mice were significantly susceptible to challenge and increased dissemination of viable C. albicans to deeper tissues, BALB/c mice were able to retain and clear the challenge in the lungs. Moreover, BALB/c mice displayed higher titers of serum and mucosal anti-C. albicans immunoglobulin A than DBA/2 mice.

Author: Dougan, Gordon, Londono, Patricia, Gao, Xiao M., Bowe, Francis, McPheat, William L., Booth, George G.
Publisher: Society for General Microbiology
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 1998
Mice, Mice (Rodents), Candida albicans, Respiratory tract diseases

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Subjects list: Research
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