The regulation of mesodermal progenitor cell commitment to somitogenesis subdivides the zebrafish body musculature into distinct domains

Article Abstract:

Study is conducted to show that a subset of mesodermal progenitor cells (MPCs) are set aside very early in zebrafish development and programmed to cell-autonomously enter the tail domain beginning with the 16th somite. The trunk is subdivided into two domains and entry into the anterior trunk, posterior trunk and tail is regulated by interactions between the Nodal and bone D(Bmp) pathways.

Washington, Cells, Morphogenesis, Cell transplantation

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Medical floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a

Article Abstract:

A study was conducted to show that the growth factor Midkine-a, expressed in the paraxial mesoderm, is required in the formation of the medial floor plate in zebrafish. It is concluded that in zebrafish, trunk-derived signals are required for complete medial floor plate (MFP) formation from a common pool of organizer-derived midline precursor cells.

Axons, Genetic research

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Gravin regulates mesodermal cell behavior changes required for axis elongation during zebrafish gastrulation

Article Abstract:

The study carried out on zebrafish embryos, suggests the possible inhibiting ability of Gravin in metastatic cells.

Animal embryology

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