Transcription factors and DNA replication origin selection

Article Abstract:

The specificities of initiator proteins that bind to the DNA and promote its replication are studied and the importance of transcription factors in the origin selection process is discussed. The findings indicate that transcription factors control some of the potential origins while others are suppressed or activated by the general chromatin structure after the early embryonic stage and they also enable the cell to regulate the origin selection process in response to extra and intra cellular signals.

Genetic aspects, Chromatin, Natural selection, DNA replication

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The transcriptome: malariologists ride the wave

Article Abstract:

The effect and the advantages of transcriptional analyses in malarioligists work are studied. The informative papers on plasmodial transcriptome by Le Roch et al (1) and Bozdech et al. (2003)(2) is taken as a the basis for this study and it is observed that the future research will be based on the relationship between genomics and proteomics.

Genetic research

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Functional genomics studied by proteomics

Article Abstract:

Proteins need to be analyzed by proteomic techniques. Two techniques, in particular, have dominated the proteomic field, two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and mass spectrometry (MS0. Two strong features are recognized, unique protein resolution and suitability for quantitative measurements.

Gel electrophoresis, Genomics, Polyacrylamide

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