Transcriptional and functional analysis of oxalyl-coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes from Lactobacillus acidophilus

Article Abstract:

A study about an operon containing genes homologous to a formyl coenzyme A transferase gene (frc) and an oxalyl coenzyme A decarboxylase gene (oxc) that was in the genome of the probiotic bacterium Lactobacillus acidophilus is presented. Physiological analysis of a mutant harboring a deleted version of the frc gene confirmed that frc expression specifically improves survival in the presence of xalic acid at pH 3.5 compared with survival of the wild-type strain.

Genetic aspects, Lactobacillus acidophilus, Coenzymes, Decarboxylases

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Characterization of superoxide dismutase in Streptococcus thermophilus

Article Abstract:

Microbiological research shows that manganase-containing superoxide dismutase enzyme from the gram-positive facultative anaerobe Streptococcus thermophilus AO54 is insensitive to cyanide poison and modified hydrogen peroxide treatment. Its expression is three or four times greater in the stationary phase of the growth cycle. Growth phase analysis is discussed.

Streptococcus, Superoxide dismutase

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Expression of a heterologous manganese superoxide dismutase gene in intestinal lactobacilli provides protection against hydrogen peroxide toxicity

Article Abstract:

The potential advantages of providing heterologous superoxide dismutases (SODs) to some of the intestinal lactobacilli are examined. It was seen that the enzyme provided clear protection against the inhibitory effect of hydrogen peroxide on the growth of Lactobacilli gasseri and L. acidophilus.

Growth, Lactobacillus, Company growth, Manganese (Nutrient)

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