Two alpha(1-3) glucan synthases with different functions in Aspergillus fumigatus

Article Abstract:

Two AGS genes of Aspergillus fumigatus (AGS1 and AGS2), which are highly homologous to those of Schizosaccharomyces pombe, with different functions are described. In vivo virulence analysis using an original method of mixed infection showed that a 50% reduction in the content of the cell wall alpha(1-3) glucan does not play a significant role in Aspergillus fumigatus pathogenicity and these altered phenotypes are not associated with a modification of virulence.

Saccharomyces, Glucans

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Generation and phenotypic characterization of Aspergillus nidulans methylisocitrate lyase deletion mutants: Methylisocitrate inhibits growth and conidiation

Article Abstract:

The propionate metabolism of Aspergillus nidulans was studied to sole the contradiction between carbon source and preservative effect and it revealed the methylcitrate cycle as the responsible pathway. Methylisocirate lyase is one of the key enzymes of the cycle and it catalyzes the cleavage of methylisocitrate into succinate and pyruvate and completes the alpha-oxidation of propionate.

All Other Basic Organic Chemical Manufacturing, Industrial Organic Chemicals, Succinates, Metabolism, Chemical properties, Methyl groups, Methyl compounds

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Construction of a genetically modified wine yeast strain expressing the Aspergillus aculeatus rhaA gene, encoding an alpha-L-Rhamnosidase of enological interest

Article Abstract:

The expression of the gene encoding A. aculeatus RhaA in a commercial wine yeast strain was investigated. The data indicate the biotechnological feasibility of the combination of wine yeast strains producing alpha- L-rhamnosidase of enological relevance.

Yeast fungi, Yeasts (Fungi), Genetic code

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