Ultraviolet-induced mutation and the chemical nature of the gene

Article Abstract:

The first clear proof that ultraviolet radiation causes genetic mutation was presented by Edgar Altenburg from experiments done on Drosophila in 1934. He irradiated Drosophila eggs at the polar end cap where the pole cells are transformed into germ cells. This resulted in numerous instances of recessive lethal mutations from ultraviolet radiation. During the 1940s, geneticists were divided about the genetic function of DNA. At that time, nucleic acids were supposedly composed of similar tetranucleotides and were not carriers of genetic information.

Causes of, Gene mutations, Gene mutation, Genetic aspects, DNA, Ultraviolet radiation

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The weaker sex is heterogametic: 75 years of Haldane's rule

Article Abstract:

The history of the development of a theoretical population genetic rule formulated by biologist J.B.S. Haldane in the 1920s and the merits of the many favorable and opposing views advocated by other geneticists are discussed. This genetic rule suggests that a defect of one sex may either be caused by inviability or sexual transformation. The issue of heterogametism is crucial in debates that have occurred over the validity of the rule.

Research, Haldane, J.B.S.

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Thirty years ago in genetics: prophage insertion into bacterial chromosomes

Article Abstract:

The model for prophage insertion into the host chromosome during lysogenization was proposed in 1963. This led to a better understanding of the chromosome structure and it has also been the first well-described programmed DNA rearrangement. Moreover, the prophage insertion proposal opened new possibilities in genetic research which includes studies on the insertion of transposable elements.

Insertion elements, DNA, DNA insertion elements

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