Yeast telomeres exert a position effect on recombination between internal tracts of yeast telomeric DNA

Article Abstract:

Yeast telomeres affect recombination between internal tracts of yeast telomeric DNA positively. In the yeast Saccharomyces cerevisiae proximity to a telomere has an effect on replication and transcription of adjacent DNA. Telomeres have a position effect on mitotic recombination. Possibly the recombination inhibitor protein blocks recombination involving endogenous telomeres.

Analysis, Genetic aspects, DNA, Observations, Telomeres, Genetic recombination, Saccharomyces

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Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of S. Cerevisiae DNA helicase

Article Abstract:

Lack of the yeast Rrm3p DNA helicase causes replication defects at multiple sites within ribosomal DNA (rDNA), including at the replication fork barrier (RFB). When the RFB binding Fob1p is deleted, rrm3-generated defects at the RFB are eliminated, but defects at other rDNA sites are not affected.

Influence, Genomes, Ribosomes, Genetic research

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Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping

Article Abstract:

High-resolution genome-wide mapping of diacetylation of histone H3 at Lys 9 and Lys 14 in resting and activated human T cells by genome-wide mapping technique is reported. The data suggests that in the gene-rich regions, high levels of the H3 acetylation are present.

Chromosome mapping, T cells

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