Zipper-like interaction between proteins in adjacent daughter cells mediates protein localization

Article Abstract:

An interaction between two membrane proteins expressed in different cells of the Bacillus subtilis sporangium, the mother cell protein SpoIIIAH and the forespore protein SpoIIQ is described. The SpoIIQ-SpoIIIAH complex reaches from the mother cell cytoplasm to the forespore cytoplasm and is ideally positioned to govern the activity of engulfment-dependent transcription factors.

Bacillus subtilis, Cytoplasm

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A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomces pombe

Article Abstract:

The Schizosaccharomyces pombe genome encodes only one of each of the three major classes of proteins implicated in RNA silencing: Dicer (Dcr1), RNA-dependant RNA polymerase (RdRP; Rdp1) and Argonaute (Ago1) are studied. The RNAi machinery in S. pombe can direct both transcriptional and posttranscriptional silencing using a single Dicer, RdRP and Argonaute protein.

Human genome

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The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs

Article Abstract:

A subunit of RNA polymarase II, Rpb4p, is required for the decay of a class of mRNAs whose products are involved in protein synthesis. Rpb4p promotes the deadenylation process of specific mRNAs and recruits Pat1/Lsm1-7 to mRNAs, thus stimulating their decapping and further decay.

Protein synthesis, Protein biosynthesis, Messenger RNA, Genetic research

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