A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

Article Abstract:

Cell-size homeostasis entails a fundamental balance between growth and division. It is observed that the two potent negative regulators of Start, Sfp1 and Sch9 are activators of the ribosomal protein and ribosome biogenesis regulons, the transcriptional programs that dictate ribosome synthesis rate in accord with environmental and intracellular conditions.

Research and Development in the Physical, Engineering, and Life Sciences, Molecular Biology, Ribosomes

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Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network

Article Abstract:

A time course of chromatin immunoprecipitation followed by a microarray analysis (ChIP-on-chip) is conducted to analyze the transcriptional map of Biniou, a FoxF transcription factor. The analysis proves that Biniou is a universal regulator of the visceral muscle transcriptional network.

Physiological aspects, Genetic aspects, Chromatin, DNA microarrays, Viscera

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