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Abbott clot-busting drug may extend window of time for treating patients

Article Abstract:

Abbott Labs is pleased with the results of a study on 180 stroke patients using its new drug called prourokinase. The drug, if and when approved by the FDA, would be an alternative to heparin as an anti-clot medication. A major improvement is that the medication helps victims of stroke if administered within six hours rather than the current option, a drug from Genentech that needs to be given within three hours of the onset of the stroke. Part of the challenge with prourokinase is that it is not given intravenously, but through a catheter into the brain, meaning training and expertise would typically be found only at large teaching hospitals. Also, one side effect is greater incidence of brain hemorrhage than with heparin or Genentech's Activase.

Comment:

New stroke treatment looks promising, but NDA has not been filed yet

Author: Winslow, Ron
Publisher: Dow Jones & Company, Inc.
Publication Name: The Wall Street Journal Western Edition
Subject: Business, general
ISSN: 0193-2241
Year: 1999
Science & research, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Anticoagulant Preparations, Research, Pharmaceutical industry, Abstract, Anticoagulants (Medicine), Anticoagulants, ABT, Abbott Laboratories (Abbott Park, Illinois)

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Oxford outlines plan to improve its performance

Article Abstract:

Oxford Health Plans Inc. outlines plans to improve its performance. The plan is aimed at returning the health maintenance organization to break even financial performance within 12 months. It will bring higher rates for employers, less flexibility for patients and lower fees for physicians and other providers. "Oxford is walking a very fine line between balancing its needs to restore profitability and going against the branded name it has established," said Bob Braddick, a consultant with William M. Mercer Inc.

Comment:

Oxford outlines plans to improve its performance

Author: Winslow, Ron, Jeffrey, Nance Ann
Publisher: Dow Jones & Company, Inc.
Publication Name: The Wall Street Journal Western Edition
Subject: Business, general
ISSN: 0193-2241
Year: 1998
Strategy & planning, Health Care and Social Assistance, Company Planning/Goals, Health, Education & Welfare, Oxford Health Plans Inc., Article

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Subjects list: United States
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