In search of a painkiller free of side effects

Article Abstract:

Adolor Corp. (Malvern, PA) has managed to raise about $20.8 million to use in financing its resarch and development program which seeks to find a replacement for morphine, and already having obtained licenses to newly cloned pain receptors from the brain. Most major drug concerns have given up several decades ago on their work with analgesics as a replacement for morphine. An interesting aspect which company researchers have found out about peripheral receptors is that the brain can distinguish between pain and an itch, so it may be possible to also block pain as well as an itch. There is a compound that has been found effective for itching. It is hoped that Aldor will have the compound in clinical testing by the end of 1998. The goal is to have ADL2-1294 developed into a topical product.

Comment:

Adolor Corp. raises about $20.8 million for continuing financing of R&D into replacement for morphine analgesic pain medicine

Pharmaceutical Preparation Manufacturing, Narcotic Analgesics NEC, Opioids, Adolor Corp.

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Giving bolts a new twist

Article Abstract:

Ultrafast Inc. of Malvern, PA, has developed "smart" bolts that tell the user how tight they are. The bolts have built-in transducers, which measure the bolts' tensile load, or tightness. The transducer does this by sending an ultrasonic from one end of a bolt to the other and back and measuring the time of flight. The company developed the technology with grants from the Ben Franklin Partnership and the NASA. Potential applications of smart bolts are tighter and less expensive planes and cars.

Comment:

Develops "smart" bolts that tell the user how tight they are

Bolt, Nut, Screw, Rivet, and Washer Manufacturing, Bolts, Nuts and bolts, Article, Ultrafast Inc.

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Digital solution to a medical problem

Article Abstract:

Brian Sweigard, junior at Pennsylvania State University developed a Web-based computer program to improve chronically ill patients in the practices of Abington Memorial Hospital and won a national patient-safety award. The program allows patients to review their clotting levels online and has produced better results than ever before among Abington's 27 physicians practices.

Care and treatment, Innovations, Product development, Medical students, Chronically ill, Professional medical/diagnostic software, Medical diagnostic software, Sweigard, Brian

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