Structural genomics and its importance for gene function analysis

Article Abstract:

The determination of all possible protein folds is the goal of structural genomics. This new approach as opposed to traditional structural biology, prioritizes the determination of the protein structure prior to discovering the function.

---

Putting proteins on the map

Article Abstract:

A new approach for mapping the subcellular location of hundreds of proteins and identifying proteins that share subcellular location patterns in single cells or tissue sections is described. Detailed knowledge of the spatiotemporal distribution of all proteins expressed in a given cell type is critical to understanding the way cell type behaves and to building computational models that stimulate cell behavior.

Cell anatomy

---

Analyzing proteome topology and function by automated multidimensional fluorescence microscopy

Article Abstract:

A multidimensional microscopic robot technology for high-throughput protein colocalization studies that runs cycles of fluorescence tagging, imaging and bleaching in situ is described. Results reveal rules of hierarchical protein network organization, in which the frequency distribution of different protein clusters obeys Zipf's law, and state-specific lead proteins appear to control protein network topology and function by analyzing many cell and tissue types.

Methods, Usage, Fluorescence microscopy, Structure

Similar abstracts:

• Abstracts: Genomic integration and gene expression by a modified adenoviral vector. Genomic integration and gene expression by modified adenoviral vector
• Abstracts: Growth stocks are out of fashion but watch for the swing back. Going with the flow
• Abstracts: Year-end planning review: some advantageous techniques should only be used with care. Is an intentionally defective dynasty trust an effective estate planning tool?
• Abstracts: Who's your neighbor? New computational approaches for functional genomics? Large-scale functional analysis using peptide or protein arrays
• Abstracts: A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.