Antibody-targeted cell fusion

Article Abstract:

Antibody-targeted cell fusion that is achieved by engineering a fusogenic viral membrane glycoprotein complex is demonstrated. The findings of the study suggest that cell fusion is not limited by the receptor choice and a broad array of cell surface antigens could be used to target the process, irrespective of their particular structure.

Viral envelopes, Cell hybridization

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Bringing amyloid into focus

Article Abstract:

Amyloid binding ligands and near-infrared fluorescence imaging is used to estimate the amount of the amyloid in the brain of living mice. The deposition of amyloid in the brain can help in predating the clinical signs of Alzheimer disease, which will help in preventing the Alzheimer disease.

Care and treatment, Alzheimer's disease, Ligand binding (Biochemistry)

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Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies

Article Abstract:

The significant role of the A1 domain of von Willebrand factor (VWF-A1) in binding of human platelets by interacting with platelet receptor glycoprotein lb alpha (GPlb[alpha]) is discussed.

DNA binding proteins, Platelet activating factor

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