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Genetic selection and the lure of SIN

Article Abstract:

A biological filter has been developed that uses a modified Sindbis virus to speed up the analysis of genome sequencing data.

Author: Nolan, Garry P.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001

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Selection of insertional mutants using subgenic-resolution arrays

Article Abstract:

The authors describe a method of genome-wide analysis of quantitative growth phenotypes using insertional mutagenesis and DNA microarrays. The applicability of this high-resolution array selection in other species is discussed.

Author: Badarinarayana, Vasudeo et al
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001
Biochemistry, Research and Development in the Physical, Engineering, and Life Sciences, Illustration

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Chemical combination effects predict connectivity in biological systems

Article Abstract:

Observed variations in the connectivity of the biological systems due to different combinations of chemicals are explained. Cellular responses to combinations of chemicals reveal the connectivity of their biological targets.

Author: Nolan, Garry P., Stockwell, Brent R., Lehar, Joseph, Zimmermann, Grant R., Krueger, Andrew S., Molnar, Raymond A., Ledell, Jebediah T., Heilbut, Adrian M., Short, Glenn F., III, Giusti, Leanne C., Magid, Omar A., Lee, Margaret S., Borisy, Alexis A., Keith, Curtis T.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
Research, Metabolism, Biochemical genetics, Biological systems

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Subjects list: United States, DNA probes
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