Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors

Article Abstract:

A strategy to rationally design trans-splicing adeno-associated virus (AAV) vectors was developed in a study. The method demonstrates the use of trans-splicing vectors to efficiently express a large therapeutic structural protein and could be applicable to other large therapeutic genes or large transcription regulatory elements.

Genetic aspects, Virus-vector relationships, DNA viruses

---

Viral-mediated plant transformation gets a boost

Article Abstract:

Modifications to tobacco mosaic virus (TMV) expression vectors is described that permit efficient infection and viral replication in almost 100% of plant leaf cells. The inefficiency of viral-based systems might derive from an altered lifestyle conferred by agroinoculation, as opposed to the normal viral life cycle.

Plant cells and tissues, Plant cells, Tobacco mosaic virus

---

Similar abstracts:

• Abstracts: Managing change in higher education. Abbreviated accounts
• Abstracts: A comment on the empirical distribution of squared unexpected returns. Noncontrollable costs and optimal performance measurement
• Abstracts: A multi-case investigation of a theory of the transfer pricing process. Agency theory: a falsification perspective
• Abstracts: Similarity judgments in strategy formulation: role, process and implications. Dynamic interaction between strategy and technology
• Abstracts: Targeting cytokines to inflammation sites. A genetic approach to inactivating chemokine receptors using a modified viral protein

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.