Rational design of cytotoxic T-cell inhibitors
Article Abstract:
The de nova design of low-molecular- weight surface mimetics is described using CDB/major histocompatibility comples (MHC) class I crystal structure as a template
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
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Enhancement of tumor necrosis factor Alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
Article Abstract:
An aminopeptidase N (CD13) ligand that targets activated blood vessels in tumors is more efficient than murine TNF in decreasing tumor burden in lymphoma and melanoma animal models.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
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Use of isogenic human cancer cells for high-throughput screening and drug discovery
Article Abstract:
Isogenic cancer cell lines are used to target the genetic alterations responsible for causing disease, in developing new cancer treatments.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001
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- Abstracts: In vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET)
- Abstracts: Measuring trunk motions in industry: variability due to task factors, individual differences, and the amount of data collected
- Abstracts: High-performance affinity beads for identifiying drug receptors. Changing attitudes to biotechnology in Japan
- Abstracts: Stable correction of a genetic deficiency in human cells by an episome carrying a 115 kb genomic transgene. Efficient gene transfer to airway epithelium using recombinant Sendai virus