Gene targeting using zinc finger nucleases

Article Abstract:

Zinc finger nucleases (ZFNs) improve the efficiency of gene targeting by introducing deoxyribonucleic acid (DNA) double-strand breaks in target genes, which then stimulate the cell's endogenous homologous recombination machinery. Test results show that ZFNs can be used to create targeting frequencies of up to 20% in a human disease-causing gene.

Research, Genetic research, Nucleases, Zinc finger proteins

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The small world of metabolism

Article Abstract:

Many organisms that are now being sequenced have not had their biochemistry studied, such is the pace of genome sequencing.

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Electrochemical DNA analysis comes of age

Article Abstract:

High-density, high-throughput microarray systems may replace fluorescence as the dominant method for DNA analysis.

Brief Article

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