The challenges of in silico biology

Article Abstract:

Biologists can now study cells as systems thanks to the advent of high-throughput technologies such as genomics and proteomics.

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In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

Article Abstract:

Relating the annotated genome sequence to the physiological functions of a cell is one of the major goals in the post-genome era. Using annotated genomes, it has been proven possible to completely reconstruct metabolic networks.

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Two-dimensional annotation of genomes

Article Abstract:

The interpretation and prediction of the genotype-phenotype relationship to adopt extended description of all the chemical interaction is analyzed. Extended description of chemical interaction is caused by the gene products of a genome in the form of a two-dimensional matrix.

Research, Models, Analysis, Genotype, Genotypes, Genomes, Phenotype, Phenotypes

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