Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay
Article Abstract:
A study is conducted in which RNA labeling is used to determine the roles of m-RNA synthesis and decay in the control of gene expression during T. gondii asexual development. The result showed that the engineered uracil phosphoribosyltransferase (UPRT) expression would allow cell-specific analysis of gene expression in organisms other than T. gondii.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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Functional annotation and network reconstruction through cross-platform integration of microarray data
Article Abstract:
An approach, 2nd order expression analysis that addresses the challenge of effective integration of data by first extracting expression patterns and then analyzing them across multiple data sets is discussed. The two distinct advantages of this approach are demonstrated using the yeast model.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
User Contributions:
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