On the iTRAQ of kinase inhibitors

Article Abstract:

A new proteomics method based on kinobeads for quantitatively analyzing the on- and off-target effects of kinase inhibitors is discussed. The iTRAQ reagent is found to highly affect the binding affinities of these kinase inhibitors.

United States, Mass Spectrometers & Spectroscopy, Mass Spectrometers, Research, Usage, Protein binding, Phosphotransferases

---

Rapid identification of DNA-binding proteins by mass spectrometry

Article Abstract:

Researchers from Denmark and Germany used matrix-assisted laser desorption/ionization time-of-flight mass spectometry to identify DNA-binding proteins isolated from cell extracts conjugated onto small, paramagnetic particles.

Denmark, Germany, Drugs, Cellular Protein, In-Vitro Diagnostic Substance Manufacturing, Ion Mass Spectroscopy, Cellular proteins, Mass spectrometry

---

Similar abstracts:

• Abstracts: Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry
• Abstracts: The use of cysteine proteinase inhibitors to engineer resistance against potyviruses in transgenic tobacco plants
• Abstracts: Strategic choices of quality, differentiation and pricing in financial services. The near-collapse of LTCM, US financial stock returns, and the fed
• Abstracts: NAS report: strengthen agbio regs and relations. US food labeling policy softens. GM food singled out for labeling in the US
• Abstracts: Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.