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Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides

Article Abstract:

The inhibition of insulin-like growth factor (IGF-i) in psoriasis is hypothesized as the cause of epidermal hyperplasia which causes an increased rate of keratinocyte cell division.

Author: Wraight, Christopher J., White, Paul J., McKean, Sandra C., Fogarty, Rhys D., Venables, Daryl J., Liepe, Ingrid J., Edmondson, Stephanie R., Werther, George A.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000

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Breeding of retroviruses by DNA shuffling for improved stability and processing yields

Article Abstract:

Researchers examined a means of creating retroviruses that are able to withstand the purification and concentration steps required for manufacturing biologically-based treatments.

Author: et al, Powell, Sharon K.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
Genetic Engineering

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In defense of complete genomes

Article Abstract:

Selkov et al. were able to prove the deduced amino acid biosynthesis capabilities of Thiobacillus ferrooxidans using a 3-fold coverage genome sequence of the organism.

Author: Parkhill, Julian
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000

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Subjects list: United States, Cell disease research
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