Revealing the world of RNA interference

Article Abstract:

RNA interference (RNAi) is used as a research tool to control the expression of specific genes in numerous experimental organisms and has potential as a therapeutic strategy to reduce the expression of problem genes. The world of RNAi is introduced and an insight is provided that deals with a process that reflects an RNA world that is alive and thriving within human cells.

RNA interference

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Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks

Article Abstract:

An integrated computational-experimental approach for computing the likelihood that gene products and associated pathways are targets of a compound is described. This was carried out by filtering the mRNA expression profile of compound-exposed cells using a reverse-engineered model of the cell's gene regulatory network.

Cellular control mechanisms, Cell regulation, Messenger RNA

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A green light to expression in time and space

Article Abstract:

The article analyzes the genome-scale in worms wherein Green Fluorescent protein (GFP) reporter constructs are developed in C. elegans. This gives information on the temporal and spatial gene expressions.

Genetic aspects, Protein research, Worms, Worms (Animals)

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