Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol

Article Abstract:

The cytochrome P450 gene (CYP6AE14) from cotton bollworm that permitted the herbivore to tolerate otherwise inhibitory concentrations of cotton metabolite, gossypol, is identified. Findings show that as a glutathione-S-transferase gene (GST1) is silenced in GST1 double-stranded DNA-expressing plants, feeding insects plant material expressing dsRNA is shown to be a general strategy for triggering RNA interference and for applications in entomological research and field control of insect pests.

Herbivores, Cytochrome P-450

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RNA interference has second helpings

Article Abstract:

Researchers have carried out a detailed analysis of the short-interfering RNAs (siRNAs) generated by experimentally induced RNA interference (RNAi) in Caenorhabditis elegans, thus revealing a new class of siRNA with unique features.

Caenorhabditis elegans, Genetic research

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