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Stepwise engineering to produce high yields of very long-chain polyunsaturated fatty acids in plants

Article Abstract:

A study reports the transgenic production of significant amounts of arachidonic acid (AA) and eicosapentaenoic acid (EPA) in Brassica juncea seeds through a stepwise metabolic engineering strategy. A series of transformations with increasing numbers of transgenes are used to demonstrate the incremental production of very long chain polyunsaturated fatty acids (VLCPUFAs), achieving AA levels of upto 25% and EPA levels of upto 15% of total seed fatty acids.

Author: Guohai Wu, Truksa, Martin, Datla, Nagamani, Vrinten, Patricia, Bauer, Joerg, Zank, Thorsten, Cirpus, Petra, Heinz, Ernst, Xiao Qui
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
All Other Miscellaneous Chemical Product and Preparation Manufacturing, Chemical preparations, not elsewhere classified, Unsaturated Fatty Acids, Arachidonic acid

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Engineering the essence of plants

Article Abstract:

Researchers have described an approach for engineering plants that produce elevated levels of commercially relevant terpenoids. The efficacy of the approach is demonstrated with two sesquiterpenes and a monoterpene, suggesting that the strategy can be generally applied to produce complex plant metabolites, many of which cannot be synthesized chemically or derived from endangered species in threatened ecosystems.

Author: Bouwmeester, Harro J.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
Industrial Organic Chemicals, Cyclic Crude and Intermediate Manufacturing, Terpenes

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Engineering what comes naturally

Article Abstract:

Tissue and bone regeneration devices are discussed.

Author: Wozney, John M., Li, Rebecca H.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2003
Bone regeneration, Tissue engineering

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Subjects list: Research, United States, Analysis, Plant metabolism
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