The sweet side of biomarker discovery

Article Abstract:

The involvement of glycans in tumor progression can be used to diagnose, predict susceptibility and monitor cancer progression. Biomolecules can complement DNA and protein for early diagnosis of cancer with development of appropriate technologies for clinical translation but owing to its low detection limits, efficiency and rapid characterization capabilities, mass spectrometry remains popular technique for biomarker discovery.

Development and progression, Biological markers

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The role of companion diagnostics in the development and use of mutation-targeted cancer therapies

Article Abstract:

Genetic differences distinguish cancer cells from normal cells and hence therapeutic advances are based on agents that specifically target the products of the genes that are mutated in cancer cells. Companion diagnostic tests that would help to identify patients who are most likely to benefit from these therapies and simplify the drug discovery process are described.

Methods, Gene mutations, Gene mutation, Cancer cells

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Genetic profiteering

Article Abstract:

Clinical genetics and genetic tests are fast developing into commodities which consumers can order to find out information such as their ancestry and cancer risk. The reaction to such a development is mixed, with backers of the endeavor arguing that people have a right for such information and critics viewing them as potentially dangerous and exploitative.

Usage, Genetic screening, Genetic testing, Medical genetics

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