AIDS-driven nucleoside chemistry

Article Abstract:

The preparation and characterization of 2',3'-dideoxynucleosides and their acyclic, cyclobutyl and heterocyclic analogs were presented. Substitution, elimination and complexation processes were undertaken in forming these new nucleosides. Some of these compounds exhibited anti-HIV properties that could prove useful in the treatment of AIDS-related diseases. Furthermore, a comparative study involving a HIV reverse transcriptase inhibitor was performed to determine the viability of the compounds as AIDS treatment drugs.

AIDS (Disease), AIDS research, Organic compounds, Organic compound synthesis, Nucleoside analogs

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BODIPY dyes and their derivatives: syntheses and spectroscopic properties

Article Abstract:

The syntheses and the spectroscopic properties of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BPDIPY) dyes and their derivatives are discussed. The analysis shows that the fluorescence characteristics of these compounds can be easily altered by changing their structures.

Science & research, Cyclic crudes and intermediates, Synthetic Organic Dye and Pigment Manufacturing, Organic Colorants, Organic Dyes & Pigments, Organic Dyes, Observations, Optical properties, Fluorescent chemicals, Chemical properties

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Syntheses of nucleoside triphosphates

Article Abstract:

Research into syntheses of some nucleoside triphosphate analogues is presented. This approach is designed to show how synthetic methods for obtaining nucleoside triphosphates have been used in different ways.

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