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Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis)

Article Abstract:

Neurological disorders of cognitive abnormalities, collectively known as neurodegenerative diseases imply the presence of excess misfiled proteins causing neuronal damage such as Alzheimer's and prion diseases, and Parkinson's diseases and amyotrophic lateral sclerosis. In all these disorders, copper-containing proteins that are normally soluble convert into insoluble aggregates by impaired copper homeostasis that can form intractable and frequently toxic deposits in brain, skeletal and muscular tissue, in the heart and the liver.

Author: Gaggelli, Elena, Kozlowski, Henryk, Valensin, Daniela, Valensin, Gianni
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 2006
Analysis, Copper (Nutrient), Homeostasis, Chemical properties, Neurodegenerative diseases

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Photoprocesses of copper complexes that bind to DNA

Article Abstract:

A study was conducted to examine the photophysical features of copper complexes that support DNA-binding interactions. Several factors influence luminescence studies involving copper phenanthrolines and DNA, including solubility and oxygen sensitivity. Free-base copper porphyrin is characterized by protonated nitrogens while the lifetime of photoexcited copper increases in methylcyclohexane as the temperature ranged from 298 to 150 degrees K.

Author: McMillin, David R., McNett, Kristina M.
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1998
Genetic aspects, DNA

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Photoluminescence properties of multinuclear copper (I) compounds

Article Abstract:

A new study investigates the photophysical behaviour of luminescent multinuclear copper (I) compounds.

Author: Cariati, Elena, Ford, Peter C., Bourassa, James
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
Luminescence

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Subjects list: Research, Copper compounds
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