High-throughput and parallel screening methods in asymmetric hydrogenation

Article Abstract:

Asymmetric hydrogenation has been extensively used in the chemical and pharmaceutical industry and it has also triggered development of many other enantioselective catalytic transformations. The process chemists look for development time, catalyst activity, process intensification, high-throughput and fast screening when determining the cost-effectiveness of a process solution for the commercial production using asymmetric hydrogenation.

Hydrogenation

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Polycyclic polyprenylated acylphloroglucinols

Article Abstract:

Active polycyclic polyprenylated acylphloroglucinols (PPAPs) are isolated from Guttiferae plants in either or both enantiomeric forms. The structure and chemical synthesis of PPAPs are discussed.

Kentucky, Clusiaceae

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Small-molecule H-bond donors in asymmetric catalysis

Article Abstract:

The rapid progress and discovery of diverse H-bond donor motifs as a small-molecule chiral catalyst used in enantioselective reactions is reviewed.

Observations, Chirality, Hydrogen bonding, Hydrogen bonds, Chemical properties

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