Resorcinolic lipids, the natural non-isoprenoid phenolic amphiphiles and their biological activity

Article Abstract:

The biological activities of phenolic lipids derived from resorcinols or higher homologues of orcinol have been studied. These lipids are found to occur naturally in 11 families of higher plants, five lower plant families and three families of bacteria. They are used in catalyzing the semi-synthesis of various compounds such as long-lasting hydrophobic antiinflammatory drugs or analogues of cannabinoids. They are also used in treating various conditions from desensitization to obesity.

Physiological aspects, Lipids, Resorcinols

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The 'Stealth' liposome: A prototypical biomaterial

Article Abstract:

Complex in vivo characteristics of liposomes based on its mechanical, chemical, and colloidal properties determines the in vivo reactivity, stability, and interaction of liposomes. An encapsulated drug in the Stealth liposome system avoids rapid uptake by the cells of reticuloendothelial system (RES) and is able to deliver drug to the target sites in the body. The encapsulation into Stealth liposomes provides a new drug delivery vehicle similar to the delivery of anticancer drugs.

Liposomes

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Introduction: molecular recognition

Article Abstract:

Molecular recognition covers a set of phenomena which are controlled by specific noncovalent interactions. Such phenomena are important in biological systems and were foreseen to create new technologies but, they are poorly understood. Undefined list of noncovalent interactions involved in recognition events and poor appreciation of noncovalent forces competition in complex systems were found to create the recognition mystery.

Protein folding

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