Ethanolamine oleate for esophageal varices
Article Abstract:
Esophageal varices are dilated, swollen and twisted veins in the esophagus, a muscular tube connecting the mouth to the stomach. Sclerosing agents, which cause thickening of the layers of the blood vessel wall, are injected into the affected veins or varices. Ethanolamine oleate was recently approved for use in the United States for treating bleeding esophageal varices. Several small studies have reported that ethanolamine is as effective as other sclerosing agents commonly used in Europe. Sclerosing agents such as ethanolamine cause inflammation in the endothelium, or inner layer of blood vessels, which results in the formation of thrombi, or blood clots, and the termination of bleeding. After several weeks or months, the wall of the blood vessel undergoes tissue deterioration and fibrosis, the development of fiber-like tissue; this results in the elimination of the varices. Studies have demonstrated that ethanolamine effectively controls sudden esophageal bleeding, prolongs survival, prevents the recurrence of bleeding, and decreases death due to bleeding esophageal varices. It may also be useful as a preventive treatment for destroying varices before they bleed. The adverse effects, which occur in 10 to 15 percent of patients, and recommended doses of ethanolamine are described. Ethanolamine oleate may be used as a sclerosing agent to treat bleeding esophageal varices. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1989
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Midodrine for orthostatic hypotension
Article Abstract:
Midodrine seems to be effective in treating the symptoms of orthostatic hypotension, helping patients maintain normal blood pressure while standing. Midodrine hydrochloride, which is marketed as ProAmatine by Roberts, increases resistance of the peripheral blood vessels, and may supplant sympathomimetics which stimulate the heart or central nervous system. Supine hypertension is the most serious possible side effect, although such minor ones as various unpleasant skin sensations are relatively common.
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1997
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A shelf life
Article Abstract:
The work of Claire Paterson is presented, with focus on her passion for reviving and re-marketing forgotten books. Particular attention is given to Paterson's effort to re-publish 'A Month in the Country', a novel by J.L. Carr.
Publication Name: Vogue
Subject: Fashion and beauty
ISSN: 0042-8000
Year: 2000
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