Dietary lipids and immune function

Article Abstract:

Obesity and high-fat diets reduce immunocompetence, increasing the probability of infection and the possibility of cancer. Variable immunodeficiency was reported in a group of overweight children, teenagers and adults. High-fat diets are also known to depress immunocompetence in animals. Immunodeficiency results from the failure of lymphocytes to respond to mitosis-promoting T-cell factors in subjects with high fat intake. Unsaturated fats are also known to reduce T-cell activity as reflected in the delayed hypersensitivity to antigens.

Dietary fat

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Vitamins and immunity

Article Abstract:

Vitamin deficiencies exacerbate the deleterious consequences of infectious diseases because it adversely affects immune responses. Carotenoids (vitamin A) such as lycopenes are known to enhance immunity from pathogens and tumors. Similar effects have been documented for vitamins D, C and E. Morbidity and mortality rates in vitamin-deficient patients are considerably reduced after the administration of supplementary vitamins. However, these observations have not been applied extensively.

Vitamin deficiency, Avitaminosis

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Immunosuppression and alteration of resistance to pulmonary tuberculosis in guinea pigs by protein undernutrition

Article Abstract:

Guinea pigs were fed differential protein levels in isocaloric diets and were injected with Mycobacterium tuberculosis after immunization with Mycobacterium bovis BCG vaccine. Results showed that resistance to tuberculosis was adversely affected by protein deficiency in guinea pigs. Protein deficiency induced disorders in T-cell functions and reduced the resistance imparted by the vaccine to the test animals.

Protein deficiency

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