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A 33-year-old man with a sore throat followed by swelling and pain in the leg

Article Abstract:

A 33-yr-old man was diagnosed with a Streptococcus pyogenes infection with compartment syndrome and toxic shock syndrome. Streptococcus pyogenes is a bacteria. Compartment syndrome is condition in which increased tissue pressure in a confined space causes decreased blood flow resulting in pain, muscle weakness and loss of sensation in the area. Toxic shock syndrome is a severe illness characterized by a high fever, vomiting, diarrhea, muscle pain and, sometimes, shock. He was hospitalized because of fever and pain in his right leg. Eleven days before admission he had a sore throat and slight fever that lasted about three days. At the hospital, examination revealed a reddened chest and right leg pain with red, tender areas. His temperature continued to rise and his right calf doubled in size. Over several hours, the leg pain increased and sensation in the right foot disappeared. Cultures of muscle tissue, throat secretions and blood showed Streptococcus pyogenes.

Author: Brennick, Jeoffry B., Barza, Michael J., Carter, Edwin L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
Streptococcal infections, Causes of, Complications and side effects, Toxic shock syndrome, Compartment syndrome, Compartment syndromes

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Tanapox infection in a college student

Article Abstract:

The case of a 21-year-old US college student is described who became infected with a virus called tanapox virus after she spent eight weeks caring for orphaned chimpanzees in the Republic of Congo. This is only the fifth case of tanapox virus infection reported in the US. Although this virus belongs to the same family as the smallpox virus, it is not dangerous and most patients recover completely even without treatment.

Author: Klaus, Sidney N., Goldsmith, Cynthia S., Kline, Richard, Dhar, A. Damian, Werchniak, Andrew E., Li, Yu, Brennick, Jeoffry B., Damon, Inger
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
New Hampshire, Case studies, Virus diseases

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A new arenavirus in a cluster of fatal transplant-associated diseases

Article Abstract:

A study to examine the causes of a febrile illness that led to the death of patients who had received organ transplants from a single donor is conducted. Results reveal a new previously unknown arenavirus that was transferred from donor to recipient as the cause of the febrile illness that proved fatal.

Author: Egholm, Michael, Birch, Chris, Goldsmith, Cynthia S., Zaki, Sherif R., Paddock, Christopher D., Wun-Ju Shieh, Conlan, Sean, Simons, Jan Fredrik, Marshall, John, Palacios, Gustavo, Druce, Julian, Tran, Thomas, Briese, Thomas, Phenix-Lan Quan, Hui, Jeffrey, Catton, Mike, Lipkin, W. Ian
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2008
United States, Health aspects, Patient outcomes, Transplantation of organs, tissues, etc., Organ transplantation, Nosocomial infections, Cross infection, Arenaviruses, Clinical report

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